Computational anatomical animal models :methodological developments and research applications /

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"Version: 20181201"--Title page verso.Includes bibliographical references.part I. Computational models. 1. Historical development and overview of computational animal models -- 1.1. Introduction -- 1.2. Construction of computational models -- 1.3. Overview of existing computational animal models -- 1.4. Popular simulation tools for computational models -- 1.5. Summary2. Design and construction of computational animal models -- 2.1. Introduction -- 2.2. Mathematical phantoms -- 2.3. Voxel-based phantoms -- 2.4. BREP phantoms -- 2.5. Summary and future perspectives3. Overview of computational mouse models -- 3.1. Introduction -- 3.2. Construction of computational mouse models -- 3.3. History of computational mouse models -- 3.4. Simulation tools used with the computational mouse models -- 3.5. Applications of computational mouse models -- 3.6. Summary4. Overview of computational rat models -- 4.1. Introduction -- 4.2. Overview of existing rat models -- 4.3. Development and application of HUST computational rat models -- 4.4. Summary5. Overview of computational frog models -- 5.1. Introduction -- 5.2. History and construction of computational frog models -- 5.3. Monte Carlo simulations with computational frog models -- 5.4. Summary6. Overview of computational canine models -- 6.1. Introduction -- 6.2. General steps for developing canine models -- 6.3. Current status of canine models -- 6.4. Summary and future perspectives7. Overview of computational rabbit models -- 7.1. Introduction -- 7.2. Construction of rabbit models -- 7.3. Model refinement -- 7.4. Examples of electromagnetic and thermal dosimetry -- 7.5. Summary8. Overview of other computational animal models -- 8.1. Introduction -- 8.2. Computational models of trout -- 8.3. Computational models of crabs -- 8.4. Computational models of flatfish -- 8.5. Computational models of bees -- 8.6. Computational models of deer -- 8.7. Computational models of earthworms -- 8.8. Computational models of ducks -- 8.9. Computational models of goats -- 8.10. Computational models of pigs -- 8.11. Computational models of non-human primates -- 8.12. Summary9. Simulation tools used with preclinical computational models -- 9.1. Introduction -- 9.2. Tools used for simulation -- 9.3. The Monte Carlo simulation method -- 9.4. Monte Carlo packages for preclinical studies -- 9.5. Comparison of performance of Monte Carlo packagespart II. Applications in preclinical research. 10. Applications of computational animal models in ionizing radiation dosimetry -- 10.1. Introduction -- 10.2. Fundamentals of radiation dosimetry -- 10.3. Applications in ionizing radiation dosimetry -- 10.4. Discussion11. Computational animal phantoms for electromagnetic dosimetry -- 11.1. Introduction -- 11.2. Minimal requirements for EM dosimetry -- 11.3. Methods -- 11.4. Outlook -- 11.5. Conclusions12. Applications of computational animal models in imaging physics research -- 12.1. Introduction -- 12.2. Computational animal models in imaging physics -- 12.3. Applications of computational animal models in imaging physics research -- 12.4. Summary and future directions13. Applications of computational animal models in radiation therapy research -- 13.1. Introduction -- 13.2. Design of digital mouse phantoms -- 13.3. Monte Carlo simulation platforms -- 13.4. Simulation of head of accelerators and energy spectra -- 13.5. Types of absorbed doses calculated in digital mouse models -- 13.6. Recommendations by collaborative working groups and agencies -- 13.7. Differences between human organs and digital mouse organs in radiation therapy -- 13.8. Excerpts of applications in digital mouse radiotherapy/dosimetry -- 13.9. Conclusions14. Summary and future outlook -- 14.1. Summary -- 14.2. Future outlook -- 14.3. Acknowledgement.Computational Anatomical Animal Models: Methodological developments and research applications provides a comprehensive review of the history and technologies used for the development of computational small animal models with a focus on their application in preclinical imaging and experimental radiation therapy, as well as non-ionizing and ionizing radiation dosimetry calculations. It also provides an overview of the overall process involved in the design of these models, including the fundamental elements used for the construction of different types of computational models, the identification of original anatomical data, the simulation tools used for solving various computational problems and the applications of computational animal models in preclinical research. Part of IPEM-IOP Series in Physics and Engineering in Medicine and Biology.Also available in print.Mode of access: World Wide Web.System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader.Professor Habib Zaidi is chief physicist and head of the PET Instrumentation & Neuroimaging Laboratory at Geneva University Hospital and faculty member at the medical school of Geneva University. He is also a professor of medical physics at the University of Groningen, adjunct professor of medical physics and molecular imaging at the University of Southern Denmark and visiting professor at IAS/University Cergy-Pontoise.Title from PDF title page (viewed on January 16, 2019).

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Publisher

: .,

Collation

1 online resource (various pagings) :illustrations (chiefly color).

Language

English

ISBN/ISSN

9780750313445

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739.27

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Subject(s)

Biomedical engineering.
TECHNOLOGY & ENGINEERING / Biomedical.
Animal models in research
Disease Models, Animal.
Models, Theoretical.

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Habib Zaidi.

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