Modeling and simulating cardiac electrical activity /

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Modeling and simulating cardiac electrical activity /

Institute of Physics (Great Britain), - Personal Name; Krogh-Madsen, Trine, - Personal Name; Christini, David J., - Personal Name;

"Version: 20201201"--Title page verso.Includes bibliographical references.1. Quantitative description of cardiac action potentials / Trine Krogh-Madsen and David J Christini -- 2. Modeling the molecular details of ion channels / Kathryn Mangold and Jonathan R. Silva -- 3. Modeling cardiac calcium signaling, regulation, and control / Andrew G. Edwards and Eleonora Grandi -- 4. Cardiac cell modeling / Claire Yanyan Ji, Elizabeth M. Cherry and Flavio H. Fenton -- 5. Modeling cardiomyocyte signaling pathways / Daniel Gratz, Alexander Winkle, Amara Greer-Short and Thomas J. Hund -- 6. Modelling cardiomyocyte energetics / Edmund J. Crampin, Michael Pan, Kenneth Tran, Shourya Ghosh and Vijay Rajagopal -- 7. Tissue and organ scale modeling : coupled cells, wave propagation, simulated arrhythmia / Edward J. Vigmond -- 8. Clinical translation of patient-specific organ level cardiac models / Caroline Mendonca Costa, Caroline Roney, Marina Strocchi Orod Razeghi and Steven Niederer.This book provides a thorough introduction to the topic of mathematical modeling of electrical activity in the heart, from molecular details of ionic channel dynamics to clinically derived patient-specific models. It discusses how cellular ionic models are formulated, introduces commonly used models and explains why there are so many different models available. The chapters cover modeling of the intracellular calcium handling that underlies cellular contraction as well as modeling molecular-level details of cardiac ion channels, and also focus on specialized topics such as cardiomyocyte energetics and signalling pathways. It is an excellent resource for experienced and specialised researchers in the field, but also biological scientists with a limited background in mathematical modelling and computational methods. Part of Biophysical Society-IOP series.Graduate students or other trainees entering research areas within the field of computational cardiology, biologists or other scientists with limited background knowledge on mathematical modeling.Also available in print.Mode of access: World Wide Web.System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader.Trine Krogh-Madsen received an MSc degree in applied physics from The Technical University of Denmark and a PhD degree in physiology from McGill University. She is an Associate Research Professor in the Department of Medicine and at the Institute for Computational Biomedicine at Weill Cornell Medicine, New York. David J. Christini received a BS degree in electrical engineering from the Pennsylvania State University and MS and PhD degrees in biomedical engineering from Boston University. After nearly twenty years as faculty member at Weill Cornell Medicine, he is currently a Professor of Physiology & Pharmacology at SUNY Downstate Health Sciences University, Brooklyn NY, where he also serves as Senior Vice President for Research.Title from PDF title page (viewed on January 14, 2021).

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Series Title: -
Call Number: -
Publisher: : .,
Collation: 1 online resource (various pagings) :illustrations (some color).
Language: English
ISBN/ISSN: 9780750320641
Classification: 612.171
Content Type: -
Media Type: -
Carrier Type: -
Edition: -
Subject(s): Biophysics.
SCIENCE / Life Sciences / Biophysics.
Models, Theoretical.
Heart
Heart Conduction System
Electrocardiography.
Specific Detail Info: -
Statement of Responsibility: edited by Trine Krogh-Madsen and David J. Christini.

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